Coxsackievirus B3–Mediated INTS10 Cleavage: A Strategic Mechanism Driving Viral Replication #AcademicAchievements #GlobalResearchAwards
Coxsackievirus B3 (CVB3) is a clinically significant enterovirus responsible for a wide spectrum of human diseases, including viral myocarditis, pancreatitis, and meningitis, making it a major subject of global virology and biomedical research 🧬. Recent molecular investigations have revealed a sophisticated viral strategy in which CVB3 hijacks host cellular machinery to enhance its own replication efficiency. Central to this mechanism is the targeted cleavage of Integrator Complex Subunit 10 (INTS10) by the viral 3C protease, a multifunctional viral enzyme essential for polyprotein processing and host modulation. This discovery highlights how CVB3 disrupts host transcriptional regulation to create a cellular environment favorable for viral propagation, a finding that has drawn increasing attention in the global research community 🌍. Studies highlighted and recognized through platforms such as Academic Achievements underscore the importance of such molecular insights in advancin...
